In the field of clinical epigenetics, mass spectrometry is integrated into our automated workflow. Likewise, mass spectrometry is an irreplaceable analytical method for the elucidation of fatty acid structures and ezymes as well as amino acids. As MS-based laboratory diagnostics in clinical epigenetics is much more complex and time-consuming, new fragmentation techniques and the development of automatable preparation and analysis steps will help to meet the growing demands from research, development and practice.
GC/MS meets the (partly legal) requirements for increasingly sensitive and informative methods in clinical analytics. Especially in the screening of proteins, the results of immunological methods are secured and verified with the help of GC/MS.
This concerns in the IGL laboratory among other things:
- Quantification of DNA adducts
- Screening amino acids and fatty acid profile in erythrocyte membranes
- Quantifications of lymphocyte sensitivity tests
- Quality assurance of split samples